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KMID : 0378019730160060057
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New Medical Journal
1973 Volume.16 No. 6 p.57 ~ p.62
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Electron Microscopic Observatios of Candida albicans Treated with Antibiotics
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高春明/Koh, Choon-Myung
崔泰周/등永健/Choi, Tae-Joo/Deung, Young-Kun
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Abstract
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The present study is an ultrafine structure of Candida albicans treated with Siccanin and Azalomycin F by means of electron microscopy.
The results as follows:
1. In contrast to the bacteria, the normal Candida albicans contains nuclear envelop, mitochondria, endoplasmic reticulum, distinct cell wall, cell membrane and nucleus as observed in the eucaryotic cells.
2. Treated Candida albicans with Siccanin and Azalomycin-F was changed their morphology and cytoplasmic components, for examples, thicking of cell wall, partial delation of nuclear envelop, mictochondria, detachment of cell membrane from cytoplasm and increasing of lipid particles.
3. When the cells were treated with the tested antibiotics at 10 mcg per ml. for 60 minutes, the cellular damges were most severe.
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